[1]姜兴茂,李亚情,张涛.纳米二氧化硅的制备及在生物医学领域的应用[J].常州大学学报(自然科学版),2015,(02):39-44.[doi:10.3969/j.issn.2095-0411.2015.02.009]
 JIANG Xing-mao,LI Ya-qing,ZHANG Tao.Preparation of Nano-Silica and Its Applications in Biomedicine[J].Journal of Changzhou University(Natural Science Edition),2015,(02):39-44.[doi:10.3969/j.issn.2095-0411.2015.02.009]
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纳米二氧化硅的制备及在生物医学领域的应用()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2015年02期
页码:
39-44
栏目:
材料科学与工程
出版日期:
2015-04-25

文章信息/Info

Title:
Preparation of Nano-Silica and Its Applications in Biomedicine
作者:
姜兴茂李亚情张涛
(常州大学 纳米结构材料实验室,江苏 常州 213164)
Author(s):
JIANG Xing-maoLI Ya-qing ZHANG Tao
(Laboratory of Nanostructured Materials,Changzhou University,Changzhou 213164,China)
关键词:
纳米二氧化硅微球制备生物医学生物安全性毒性
Keywords:
silica nanopaticlessynthesisbiomedicinebiosafetytoxicity
分类号:
O 647.33
DOI:
10.3969/j.issn.2095-0411.2015.02.009
文献标志码:
A
摘要:
综述了近几年来纳米二氧化硅的一些主要制备方法,例如:Stber法、模板法、微乳液法、气溶胶法。并且简述了纳米二氧化硅在抗菌剂、药物缓释等生物医学领域中的应用,以及纳米二氧化硅微球的浓度、粒径大小、表面性质等方面对纳米二氧化硅的生物安全性的影响。介绍了无定型纳米二氧化硅的毒性与其结构的关系,同时指出了单分散纳米石英颗粒的制备还存在许多亟待解决的难点。
Abstract:
The preparation methods of nano-silica have been reviewed such as Stber method,template process,micro-emulsion method,sol-gel process.This paper has summarized the applications of nano-silica in biology and medicine,including antimicrobial,drug release,and the impact of concentration,particle size and surface properties,etc.onthe biosafety of amorphousnano-silica.The relationship between toxicity oftheamorphousnano-silicaandtheir structurehas also been discussed.Meanwhile,there are many difficulties in the preparation of monodispersenano quartzto be solved.

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备注/Memo

备注/Memo:
国家自然科学基金(21373034,21201140,CM20133005)。
更新日期/Last Update: 2015-05-20