[1]李彦伟,魏 炜,刘凤霞,等.高压提取黄精糖类物质的工艺研究[J].常州大学学报(自然科学版),2019,31(01):80-84.[doi:10.3969/j.issn.2095-0411.2019.01.012]
　LI Yanwei,WEI Wei,LIU Fengxia,et al.Study on the Process of High-Pressure Extraction Technology of Carbohydrate Extracted from Polygonatum[J].Journal of Changzhou University(Natural Science Edition),2019,31(01):80-84.[doi:10.3969/j.issn.2095-0411.2019.01.012]
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高压提取黄精糖类物质的工艺研究()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
第31卷
期数:
2019年01期
页码:
80-84
栏目:
生物医学工程
出版日期:
2019-01-28

文章信息/Info

Title:
Study on the Process of High-Pressure Extraction Technology of Carbohydrate Extracted from Polygonatum
文章编号:
2095-0411(2019)01-0080-05
作者:
李彦伟; 魏 炜; 刘凤霞; 赵成昊; 李 皓; 刘志军
(大连理工大学 化工机械与安全学院,流体与粉体工程研究设计所,辽宁 大连 116024)
Author(s):
LI Yanwei;  WEI Wei;  LIU Fengxia;  ZHAO Chenghao;  LI Hao;  LIU Zhijun
(Research & Design Instituteof Fluid and Power Engineering, School of Chemical Machinery and Safety Engineering, Dalian University of Technology, Dalian 116024, China)
关键词:
高压提取;  黄精;  糖类物质;  提取
Keywords:
high-pressure extraction;  Polygonatum;  carbohydrate;  extract
分类号:
O 621.3
DOI:
10.3969/j.issn.2095-0411.2019.01.012
摘要:
黄精中糖类物质具有降血压、降血糖、降血脂、提高免疫力等功效。采用高压提取技术,获得黄精糖类物质的提取液,通过苯酚-硫酸法测定提取液中的糖质量浓度,考察提取剂浓度、物料粒径以及操作压力对黄精提取液中糖质量浓度的影响,并与传统煎煮法进行对比。实验获得较优的工艺条件为:压力250 MPa、粒径小于0.425 mm、提取剂为水、料液比为1:20、保压时间为10 min、提取温度25℃。在此条件下,得到提取液糖质量浓度为25.3 mg/mL,而传统煎煮法提取液糖质量浓度为19.4 mg/mL。表明高压提取技术具有提取时间短、提取效率高且杂质较少等特点,在天然活性物质的提取领域具有广阔的应用前景和研究价值。
Abstract:
Modern pharmacology confirmed that carbohydrate extracted from Polygonatum could help reduce blood pressure, concentration of blood glucose, blood fat, and improve immunity. Carbohydrate was extracted by high-pressure extraction technology from Polygonatum. The mass concentrations of carbohydrate were measured by the phenol-sulfuric acid method. The effects of particle size of raw material, pressure and valume fraction of extractant on mass carbohydrate of concentration were investigated. The results showed that the optimum conditions for high-pressure extraction were pressure 250 MPa, the particle size <0.425 mm, the extractant water, the ratio 1:20, holding-pressure time 10 min, extraction temperature 25℃. Under these conditions, the concentration of carbohydrate extracted by high-pressure extraction was 25.3 mg/mL, while the concentration of carbohydrate extracted by the traditional decoction method was 19.4 mg/mL. The high-pressure extraction technique used in this study demonstrated its characteristics of shorter extraction time, higher extraction efficiency and less impurities, which has broad application prospects and research value in the extraction of natural active ingredients.

参考文献/References:


[1] 国家药典委员会. 中华人民共和国药典:第1部[M].北京:中国医药科技出版社,2015:306-307.
[2]姜程曦, 张铁军, 陈常青. 黄精的研究进展及其质量标志物的预测分析[J]. 中草药, 2017,48(1):1-16.
[3]李超彦, 周媛媛, 王福青. 黄精多糖联合低剂量顺铂对小鼠H22肝癌移植瘤生长的抑制及其抗氧化损伤作用[J]. 中国老年学杂志, 2016,36(5):1038-1040.
[4]付婷婷, 王国贤, 陈婷婷. 黄精多糖对糖尿病肾病大鼠肾脏的保护作用[J]. 中药药理与临床, 2015,31(4):123-126.
[5]李丽, 田丽娜, 任振兴, 等. 黄精多糖的结构分析及功能活性研究进展[J]. 中国实验方剂学杂志, 2015,21(15):231-234.
[6]陈婷婷, 王国贤, 付婷婷, 等. 黄精多糖对Ⅰ型糖尿病大鼠心肌炎症的保护作用[J]. 中药药理与临床, 2015,31(4):86-90.
[7]ZHANG F, ZHANG J, WANG L. Effects of polygonatum sibiricum polysaccharide on learning and memory in a scopolamine-induced mouse model of dementia[J]. NEURAL REGENERATION RESEARCH, 2008,1(3):33-36.
[8]YANG J, WU S, HUANG X, et al. Hypolipidemic activity and antiatherosclerotic effect of polysaccharide of polygonatum sibiricum in rabbit model and related cellular mechanisms[J]. Evidence-Based Complementary and Alternative Medicine, 2015,2015:1-6.
[9]王聪. 多花黄精多糖提取分离、分子量测定及其粗多糖的初步药效研究[D]. 成都: 成都中医药大学, 2012.
[10]卜红南. 黄精多糖的提取及其免疫活性研究[J]. 实用医药杂志, 2017,34(1):48-51, 56.
[11]骆文灿. 超声波辅助提取长梗黄精多糖工艺的研究[J]. 福建农业学报, 2016,31(4):431-436.
[12]JUN X. High-pressure processing as emergent technology for the extraction of bioactive ingredients from plant materials[J]. Critical Reviews in Food Science and Nutrition, 2013,53:837-852.
[13]燕继永, 庞遵霆, 张伟. 黄精复方胶囊制备工艺研究[J]. 中华中医药学刊, 2016,34(1):218-221.
[14]马宁, 杨培君. 苯酚-硫酸法测定石参多糖工艺条件的优化[J]. 陕西理工学院学报(自然科学版), 2013(5):64-70.
[15]ZENG G, ZHANG Z, LU L, et al. Protective effects of Polygonatum sibiricum polysaccharide on ovariectomy-induced bone loss in rats[J]. Journal of Ethnopharmacology, 2011,136(1):224-229.
[16]王居伟, 马挺军, 贾昌喜. 超高压提取苦荞黄酮的工艺优化及动力学模型[J]. 中国粮油学报, 2011,36(12):93-99.
[17]徐兵兵, 倪穗. 野生黄精的多糖含量测定及提取工艺研究[J]. 中国野生植物资源, 2016(4):19-22.
[18]LEE A R, CHOI S, CHOI H, et al. Optimization of ultra high pressure extraction(UHPE)condition for puffed ginseng using response surface methodology[J]. Food Science and Biotechnology, 2014,23(4):1151-1157.

备注/Memo

备注/Memo:
收稿日期:2018-09-20。
作者简介:李彦伟(1991—), 男, 蒙古族,内蒙古赤峰人,硕士生。通信联系人:刘志军(1969—),E-mail: liuzj@dlut.edu.cn
更新日期/Last Update: 2019-02-20