[1]徐光辉,朱国彪.偶氮二异丁酰（N-乙醇）胺的合成[J].常州大学学报(自然科学版),2011,(04):19-22.
　XU Guang-hui,ZHU Guo-biao.Study of the Synthesis of 2,2′-Azobis N-Ethanol-2- Methylpropionamide[J].Journal of Changzhou University(Natural Science Edition),2011,(04):19-22.
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偶氮二异丁酰（N-乙醇）胺的合成()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2011年04期
页码:
19-22
栏目:
出版日期:
2011-09-30

文章信息/Info

Title:
Study of the Synthesis of 2,2′-Azobis N-Ethanol-2- Methylpropionamide
作者:
徐光辉1; 朱国彪2
1江苏华达化工集团 生产部，江苏 常州 213033；2常州大学 江苏 省精细石油化工重点实验室，江苏 常州 213164
Author(s):
XU Guang-hui1;  ZHU Guo-biao2
1.Production Department,Jiangsu Huada Chemical Group Co. Ltd.,Changzhou 213033 ，China；2.Jiangsu Key Laboratory of Fine Petrochemicals,Changzhou University,Changzhou 213164,China
关键词:
醇解反应; 氨解反应; 偶氮二异丁酰（N-乙醇）胺; 重结晶
Keywords:
alcoholysis reaction; ammonolysis reaction; 2; 2′-azobi s N-ethanol-2-methylpropionamide; recrystallization
分类号:
TQ 314
文献标志码:
A
摘要:
以偶氮二异丁腈和甲醇为原料，经氯化亚砜催化下的醇解 反应得到偶氮2-甲基丙酸甲酯，收率906%；将该酯化物和单乙醇胺经甲醇钠催化下的氨解 反应得到偶氮二异丁酰（2-乙醇）胺，收率851%；粗产品经水重结晶得到目标产品，收率 84.5%。合成过程总收率65%以上，产品纯度994%以上。
Abstract:
2,2，-azobis 2-methyl propionate methyl ester was obtaine d with the ester yield of 90.6% by using azodiisobutyronitrile and methanol as raw materials and by alcoholysis reaction of thionyl chloride as catalyst. The a bove ester was ammonolysised with monoethanolamine to produce 2,2′-azobis N-eth anol-2-methylpropionamide with the product yield of 85.1%. The desired product was obtained by recrystallization of the above product in water with the yield o f 84.5%. The total yield of the desired product for this process is above 65% w ith the product purity above 994%.

参考文献/References:

[1]朱洪法，朱玉霞工业助剂手册［M］北京：金盾出版社，2007.
[2］章思规，章伟精细化学品及中间体手册［M］北京：化学工业出版社，2004.
[3］Kondo Suguru，Hirose Seiji，Shiraki Kazuo. Azoamide Compounds and their Use as Polymerization Initiators：EP，0957114A1［P］. 1999-11-17.
[4］Maesawa Tsuneaki，Shirki Kazuo，Shimamura Nobutaka. Azoamide Compounds and their Use for Producing Block Copolymers：US,5973125A［P］.1999-10-26.

备注/Memo

备注/Memo:
作者简介：徐光辉（1964-），男，江苏武进人，高级工 程师。
更新日期/Last Update: 2011-09-30