[1]杨 洁,杨 彦,叶 昊,等.基于生物标志物响应指数的电子废弃物拆解区人群健康风险评价[J].常州大学学报(自然科学版),2013,(02):43-47.[doi:10.3969/j.issn.2095-0411.2013.02.011]
　YANG Jie,YANG Yan,YE Hao,et al.Health Risk Assessment of People in E Waste Dismantling Area Based on Integrated Biomarker Response Index[J].Journal of Changzhou University(Natural Science Edition),2013,(02):43-47.[doi:10.3969/j.issn.2095-0411.2013.02.011]
点击复制

基于生物标志物响应指数的电子废弃物拆解区人群健康风险评价()
分享到：

常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2013年02期
页码:
43-47
栏目:
安全工程
出版日期:
2013-03-30

文章信息/Info

Title:
Health Risk Assessment of People in E Waste Dismantling Area Based on Integrated Biomarker Response Index
作者:
杨 洁; 杨 彦; 叶 昊; 叶坤孝; 李定龙
常州大学 环境与安全工程学院,江苏 常州 213164
Author(s):
YANG Jie;  YANG Yan;  YE Hao;  YE Kun xiao;  LI Ding long
School of Environmental and Safety Engineering, Changzhou University, Changzhou 213164, China
关键词:
电子废弃物;  生物标志物;  IBR;  健康风险评价
Keywords:
e-waste;  biomarker;  IBR;  health risk assessment
分类号:
X 835
DOI:
10.3969/j.issn.2095-0411.2013.02.011
文献标志码:
A
摘要:
以浙江台州某电子废弃物拆解区的帽岭、桐山、岭下周3个村人群为暴露组,以西焦湾人群为对照组,在对其8种内分泌指标(TSH、T4、FT4、T3、FT3、FSH、LH、T)检测并进行相关性分析基础上,运用综合生物标志物响应指数法开展了人群健康的影响评价。结果表明,3个村人群的FT4、FSH的浓度均低于西焦湾人群; 除岭下周外,帽岭和桐山人群的TSH、T3、FT3和T的浓度均低于西焦湾人群,T4浓度仅在桐山低于西焦湾,而LH与T4相反。TSH水平与拆解和拆解时戴手套呈正相关,T3水平与拆解和拆解时戴口罩呈正相关,FT4水平仅和拆解具有相关性; FSH、LH水平与抽烟、饮酒和戴口罩有关,T水平和抽烟、饮酒呈负相关关系; 4个村的SIBR值大小依次为桐山<帽岭<西焦湾<岭下周。
Abstract:
The villigers of Maoling,Tongshan and Lingxiazhou in an e waste dismantling area in Taizhou, Zhejiang were selected as the exposure group, and those of Xijiaowan as the control group. Based on the detection of 8 endocrine indexes(TSH,T4,FT4,T3,FT3,FSH,LH,T)and correlation analysis, the integrated biomarker response index was used to evaluate the human health. The results showed that the concentrations of FT4 and FSH of people were lower than those of people in Xijiaowan; except Lingxiazhou, the concentrations of TSH,T3,FT3 and T of people in Maoling and Tongshan were lower than those of people in Xijiaowan, and the concentration of T4 only in Tongshan was lower than that in Xijiaowan, while LH was opposite with T4. TSH level was positively correlated with disassembly and wearing gloves; T3 level was positively correlated with disassembly and wearing masks; FT4 was only correlated with disassembly; FSH and LH levels were correlated with smoking,drinking and wearing mask; T level was negatively correlated with smoking and drinking; the SIBR values of the 4 villages frow low to high were in the sequence of Tongshan,Maoling,Xijiaowan and Lingxiazhou.

参考文献/References:

[1] 孟范平,杨菲菲,程凤莲.基于生物标志物指数法的海洋环境评价方法综述[J].应用生态学报,2012,23(4): 1128-1136.
[2] Beliaeff B, Burgeot T. Integrated biomarker response: A useful tool for ecological risk assessment [J]. Environmental toxicology and chemistry, 2002, 21(6): 1316-1322.
[3] Pereira P, de Pablo H, Rosa-Santos F, et al. Metal accumulation and oxidative stress in Ulva sp. Substantiated by response integration into a general stress index [J]. Aquatic Toxicology, 2009, 91:336-345.
[4] Oliveira M, Maria V L, Ahmad I, et al. Contamination assessment of a coastal lagoon(Ria de Aveiro, Portugal)using defence and damage biochemical indicators in gill of Liza aurata An integrated biomarker approach [J]. Environmental Pollution, 2009, 157:959-967.
[5] Oliveira M, Ahmad I, Maria V L, et al. Monitoring pollution of coastal lagoon using Liza aurat kidney oxidative stress and genetic endpoints: an integrated biomarker approach [J]. Ecotoxicology, 2010, 19: 643-653.
[6] Wang C, Lu G H, Song W T, et al. Integrated biomarker response index for the assessment of environmental stress of the Yangtze River(Nanjing section)[J]. Fish Physiol Biochem, 2010, 36:1069-1078.
[7] 杨彦,于云江,李定龙,等.不同电子废弃物拆解场重金属经口暴露的健康风险研究[J].环境科学学报,2012,32(4):974-983.
[8]尹林.影响妇科疾病的产科因素分析[J].中国妇幼保健,2008,23(1):24-26.
[9] 张秋玲,周桂侠.国内铅对雌性生殖毒性的研究进展[J].工业卫生与职业病, 2008,34(2): 108-110.
[10] 浙江省统计局,国家统计局浙江调查总队.浙江统计年鉴[Z].北京:中国统计出版社, 2010: 29-30
[11] 钱春花,唐伟,刘超,等.多氯联苯对甲状腺细胞功能影响的研究[J].南京医科大学学报:自然科学版,2006,26(6):396-399.
[12] 吴伟,瞿建宏,陈家长,等.多氯联苯(PCBs)胁迫下鲫鱼肝脏EROD酶活性与血清性激素含量的相关性研究[J].生态与农村环境学报,2006,22(4):52-56.
[13] 刘浩华,伊雄海,陆贻通.内分泌干扰物莠去津对鲫鱼血清激素的影响[J].生态毒理学报,2007,2(2):184-189.
[14] 刘国红,杨克敌,刘西平,等.人体内有机氯农药残留对生殖内分泌的影响研究[J].卫生研究,2005,34(4):524-528.

备注/Memo

备注/Memo:
基金项目:国家环保部公益性行业科研专项(200909101); 国家重点基础研究发展计划(973 计划)(2008CB418205) 作者简介:杨洁(1988-),男,江苏无锡人,硕士生; 通讯联系人:李定龙。
更新日期/Last Update: 2013-03-30