[1]吴大同,孔 泳.功能性二氧化硅微球的制备及对色氨酸对映体的高效拆分研究[J].常州大学学报(自然科学版),2019,31(06):17-22.
　WU Datong,KONG Yong.Preparation of Functional Submicrometer Silica Spheres and Their Application in Eenantioseparation of Tryptophane[J].Journal of Changzhou University(Natural Science Edition),2019,31(06):17-22.
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功能性二氧化硅微球的制备及对色氨酸对映体的高效拆分研究()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
第31卷
期数:
2019年06期
页码:
17-22
栏目:
化学化工
出版日期:
2019-11-28

文章信息/Info

Title:
Preparation of Functional Submicrometer Silica Spheres and Their Application in Eenantioseparation of Tryptophane
文章编号:
2095-0411(2019)06-0017-06
作者:
吴大同; 孔 泳
(常州大学 石油化工学院,江苏 常州 213164)
Author(s):
WU Datong;  KONG Yong
(School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China)
关键词:
手性离子液体;  二氧化硅微球;  色氨酸;  手性分离
Keywords:
chiral ionic liquid;  silica sphere;  enantioseparation;  tryptophane
分类号:
O 065
文献标志码:
A
摘要:
通过将功能性离子液体共价键合到二氧化硅微球表面制备一种功能性二氧化硅微球,并作为手性拆分材料用于色氨酸对映体的拆分研究。首先,对合成的有机分子和目标材料进行了NMR,FT-IR,SEM,TGA等测试表征,并以该复合材料作为固相萃取剂选择性拆分色氨酸对映体。其次,详细筛选和优化功能性二氧化硅微球对色氨酸对映体的手性拆分条件。研究表明:在最优的分离条件下,该二氧化硅微球对色氨酸对映体具有良好的手性拆分能力,其对映体过量值最高可以达到0.93。同时,利用密度泛函理论对拆分机理进行详细研究。
Abstract:
A functional ionic liquid is synthesized and performed as modifies on the surface of submicrometer silica spheres. Next, the obtained material is characterized by using NMR, FTIR, SEM and TGA. The chiral resolution conditions for tryptophan enantiomers are analyzed and screened in detail. It is observed that the material has the excellent capability of enantioseparation for tryptophane under optimized conditions. The optimized Ee value is up to 0.93. Meantime, the mechanism is discussed by using density functional theory.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2018-11-20。
基金项目:国家自然科学基金青年基金资助项目(21804013)。
作者简介:吴大同(1990—),男,江苏南通人,博士,讲师。E-mail: wudatong@cczu.edu.cn
更新日期/Last Update: 2019-12-02