[1]唐 威,周长清,肖网琴,等.2-羟基-3-甲氧基苯甲醇的合成[J].常州大学学报(自然科学版),2013,(02):61-63.[doi:10.3969/j.issn.2095-0411.2013.02.015]
　TANG Wei,ZHOU Chang qing,XIAO Wang qin,et al.Investigation on the Synthesis of 2-Hydroxy-3-Methoxybenzyl Alcohol[J].Journal of Changzhou University(Natural Science Edition),2013,(02):61-63.[doi:10.3969/j.issn.2095-0411.2013.02.015]
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2-羟基-3-甲氧基苯甲醇的合成()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2013年02期
页码:
61-63
栏目:
出版日期:
2013-03-30

文章信息/Info

Title:
Investigation on the Synthesis of 2-Hydroxy-3-Methoxybenzyl Alcohol
作者:
唐 威1; 周长清1; 肖网琴1; 戎志峰1; 孟 启1; 2
1.常州大学 石油化工学院,江苏 常州 213164; 2.常州大学怀德学院,江苏 常州 213016
Author(s):
TANG Wei1; ZHOU Chang qing1; XIAO Wang qin1; RONG Zhi feng1; MENG Qi1; 2
1.School of Petrochemical Engineering,Changzhou University,Changzhou 213164,China; 2.Changzhou University Huaide College,Changzhou 213016,China
关键词:
2-羟基-3-甲氧基苯甲醇;  合成;  愈创木酚;  硼酸;  多聚甲醛
Keywords:
2-hydroxyl-3-methoxybenzyl alcohol;  synthesis;  guaiacol;  boric acid;  paraformaldehyde
分类号:
Q 625.31
DOI:
10.3969/j.issn.2095-0411.2013.02.015
文献标志码:
A
摘要:
研究了以愈创木酚为起始原料、经硼酸酯化后再与多聚甲醛进行羟甲基化合成2-羟基-3-甲氧基苯甲醇的方法,探讨了原料配比、反应温度、反应时间等反应条件对反应的影响。研究表明,该合成方法具有原料价廉易得、合成操作简便、产品纯度高等优点,具有一定的工业化前景。产物结构经核磁共振确认,HPLC测定产品纯度达到99.2%。
Abstract:
The synthesis of 2-hydroxyl-3-methoxybenzyl alcohol with guaiacol as the starting material through esterification reaction with boricacid and subsequent hydroxymethylation reaction with paraformaldehyde was investigated in this paper. The influence of the raw material ratio, reaction temperature, and reaction time on the reaction conditions was studied. The results showed that the methodology has the advantages of cheap raw materials, convenient operation and high purity of product(99.2% determined by HPLC). The structure ofthe product was characterized by 1H NMR.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:唐威(1988-),男,江苏启东人,硕士生; 通讯联系人:孟启。
更新日期/Last Update: 2013-03-30