[1]董 雯,王守安,陈秀娇,等.阿尔茨海默病动物模型神经行为学评价方法研究进展[J].常州大学学报(自然科学版),2018,30(05):87-92.[doi:10.3969/j.issn.2095-0411.2018.05.013]
　DONG Wen,WANG Shouan,CHEN Xiujiao,et al.Advance in Study Methods of Neurobehavioral Assessment for Animal Models of Alzheimer's Disease[J].Journal of Changzhou University(Natural Science Edition),2018,30(05):87-92.[doi:10.3969/j.issn.2095-0411.2018.05.013]
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阿尔茨海默病动物模型神经行为学评价方法研究进展()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
第30卷
期数:
2018年05期
页码:
87-92
栏目:
生物医学工程
出版日期:
2018-09-28

文章信息/Info

Title:
Advance in Study Methods of Neurobehavioral Assessment for Animal Models of Alzheimer's Disease
作者:
董 雯; 王守安; 陈秀娇; 张金添; 郑伟男; 林心怡
莆田学院 基础医学部,福建 莆田 351100
Author(s):
DONG Wen;  WANG Shouan;  CHEN Xiujiao;  ZHANG Jintian;  ZHENG Weinan;  LIN Xinyi
General Medicine Department, Putian University, Putian 351100, China
关键词:
阿尔茨海默病;  动物模型;  行为学
Keywords:
Alzheimer's disease;  animal model;  behaviourology
分类号:
R 331
DOI:
10.3969/j.issn.2095-0411.2018.05.013
摘要:
阿尔茨海默病的主要临床表现是进行性认知功能障碍和记忆损伤,相应的AD动物模型应该表现出学习和记忆能力的改变。随着科技的发展,出现多种评价该模型神经行为学的设备和方法。综述了目前研究常用的AD动物模型神经行为学评价方法,以期为今后相关研究提供参考。
Abstract:
The main clinical manifestations of Alzheimer's disease(AD)are progressive cognitive impairment and memory impairment, so the corresponding AD animal models should show the changes in learning and memory abilities. With the development of science and technology, a variety of apparatus and method are used in neurobehavioral assessment for AD animal models. Therefore, this article discusses the current methods of neurobehavioral assessment for AD animal models, in order to provide some reference for future work.

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备注/Memo

备注/Memo:
收稿日期:2017-12-20。
基金项目:福建省教育厅中青年教师教育科研项目(JAT170514); 莆田学院校内科研项目(2017072)。
作者简介:董雯,(1981—),男,福建漳州人,博士,讲师。E-mail: dw0081@yeah.net
更新日期/Last Update: 2018-09-28