[1]梁翠荣,金桂花,吴胜楠,等.点击化学应用于合成1,2,3-三唑衍生物的研究进展[J].常州大学学报(自然科学版),2015,(01):54-61.[doi:10.3969/ j.issn.2095-0411.2015.01.011]
 LIANG Cui-rong,JIN Gui-hua,WU Sheng-nan,et al.Recent Progress in Application of Click Chemistry in the Synthesis of 1,2,3-Triazoles Derivatives[J].Journal of Changzhou University(Natural Science Edition),2015,(01):54-61.[doi:10.3969/ j.issn.2095-0411.2015.01.011]
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点击化学应用于合成1,2,3-三唑衍生物的研究进展()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2015年01期
页码:
54-61
栏目:
化学化工
出版日期:
2015-01-25

文章信息/Info

Title:
Recent Progress in Application of Click Chemistry in the Synthesis of 1,2,3-Triazoles Derivatives
作者:
梁翠荣金桂花吴胜楠陆 晨陈 新
常州大学 制药与生命科学学院,江苏 常州 213164
Author(s):
LIANG Cui-rongJIN Gui-huaWU Sheng-nanLU ChenCHEN Xin
School of Pharmaceutical and Life Science,Changzhou University,Changzhou213164,China
关键词:
123-三唑 点击化学 催化剂
Keywords:
123-triazoles click chemistry catalysts
分类号:
O 626.1
DOI:
10.3969/ j.issn.2095-0411.2015.01.011
文献标志码:
A
摘要:
1,2,3-三唑是一类具有重要生物活性的杂环化合物,在医药、农药等领域都得到了广泛的应用。点击化学(click chemistry)的代表反应为铜催化的叠氮-炔基Husigen环加成反应。综述了近年来国内外学者使用不同新型催化剂和试剂进行点击化学(click chemistry),用于合成1,4-二取代、1,5-二取代和1,4,5-三取代1,2,3-三唑衍生物的研究进展。
Abstract:
1,2,3-Triazoles are a class of heterocyclic compounds withimportant biologically activities, and have been widely used in the pharmaceutical, pesticide and other fields. The traditional click chemistry is copper-catalyzed Husigen cycloaddition of azides with alkynes. This paper has summarized the recent research progress in the application of click chemistry for the synthesis of 1,4-disubstituted-, 1,5-disubstituted-and 1,4,5-trisubstituted-1,2,3-triazole derivatives by employing various new catalysts and reagents.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金面上项目(21272029)。 作者简介:梁翠荣(1989-), 女,江苏淮安人,硕士生。通讯联系人:陈新,E-mail:xinchen@cczu.edu.cn
更新日期/Last Update: 2015-01-25