[1]周晓鹰,王晶晶,刘晓骞.方酸菁染料在生物检测中的研究进展[J].常州大学学报(自然科学版),2017,(02):34-40.[doi:10.3969/j.issn.2095-0411.2017.02.007]
 ZHOU Xiaoying,WANGJingjing,LIU Xiaoqian.Research Progress on Squaraine Dyes in Bioassay Technology[J].Journal of Changzhou University(Natural Science Edition),2017,(02):34-40.[doi:10.3969/j.issn.2095-0411.2017.02.007]
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方酸菁染料在生物检测中的研究进展()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2017年02期
页码:
34-40
栏目:
生物医学工程
出版日期:
2017-03-28

文章信息/Info

Title:
Research Progress on Squaraine Dyes in Bioassay Technology
作者:
周晓鹰12王晶晶2刘晓骞2
1.英国南安普顿大学 医学院,南安普顿 SO16 6YD; 2.常州大学 制药与生命科学学院,江苏 常州 213164
Author(s):
ZHOU Xiaoying12 WANGJingjing2 LIU Xiaoqian2
1.The School of Medicine, University of Southampton, Southampton, SO16 6YD, UK; 2.School of Pharmaceutical Engineering and Life Science, Changzhou University, Changzhou 213164, China
关键词:
方酸菁染料 荧光成像 生物检测 医学诊断
Keywords:
squaraine dye fluorescence imaging bioassay medical diagnostics
分类号:
R 943
DOI:
10.3969/j.issn.2095-0411.2017.02.007
文献标志码:
A
摘要:
方酸菁是一种新型的近红外有机染料,由于其特殊的 D-A-D 结构,在可见-近红外区域有强烈的吸收和荧光发射,因而越来越多地被应用在生物检测中。综述了近年来方酸菁染料在生物检测技术中的发展和应用,也介绍了方酸菁探针的荧光成像技术在蛋白质标记和肿瘤标记与诊断中的应用,并展望了该领域的发展前景。
Abstract:
Squarylium is a new near-infrared organic dye.Due to its special structure Donor-Accept-Donor,squaraine dyes in the visible-near infrared region have a strong absorption and fluorescence emission, which have been used increasingly in biological fluorescence imaging. This article discussed the development and application of squaraine dyes in biological fluorescence imaging. The squarylium probe fluorescence imaging as markers in protein and tumoris was also introduced,as well as diagnosis drugs in tumor. Moreover, the further development prospect in this field is prospected.

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备注/Memo

备注/Memo:
收稿日期:2016-05-28。
基金项目:常州科技局国际合作研究基金资助(KYJ1520305)。
作者简介:周晓鹰(1957—),女,博士,英籍,英国南安普顿大学客座教授。
更新日期/Last Update: 2017-04-01