[1]方永勤,席化远.对氟苯甲酰氯的合成[J].常州大学学报(自然科学版),2012,(01):18-20.
　FANG Yong-qin,XI Hua-yuan.Synthesis of p-Fluorobenzoyl Chloride[J].Journal of Changzhou University(Natural Science Edition),2012,(01):18-20.
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对氟苯甲酰氯的合成()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2012年01期
页码:
18-20
栏目:
出版日期:
2012-01-01

文章信息/Info

Title:
Synthesis of p-Fluorobenzoyl Chloride
作者:
方永勤; 席化远
常州大学 设计研究院,江苏 常州 213164
Author(s):
FANG Yong-qin; XI Hua-yuan
Institute of Design and Research,Changzhou University, Changzhou 213164,China
关键词:
对氟甲苯;  光氯化;  水解;  对氟苯甲酰氯
Keywords:
p-fluorotoluene;  photochlorination;  hydrolysis;  p-fluorobenzoyl chloride
分类号:
TQ 245.2
文献标志码:
A
摘要:
以对氟甲苯为原料,经光氯化、水解、减压精馏合成对氟苯甲酰氯。对氟甲苯在光照及副反应抑制剂作用下,125-145 ℃与氯气反应合成对氟三氯甲苯,收率94.8%; 水解反应的较优工艺为:120 ℃,n(水):n(对氟三氯甲苯)=0.98:1.00,对氟苯甲酰氯收率91.5%,总收率86.7%。产品结构经红外光谱、质谱及核磁共振氢谱确认。
Abstract:
p-Fluorobenzoylchloride was synthesized with p-fluorotoluene by photochlorination, hydrolysis and vacuum distillation. In the presence of visible light and side-reaction inhibitor, p-fluorotoluene reactedwith chlorine at 125-145 ℃,the yield of p-fluorobenzotrichloride was94.8%; p-fluorotoluene reacted with water at 120 ℃, the mole ratio ofwater to p-fluorobenzotrichloride was 0.98:1, the yield of p-fluorobenzoyl chloride was 91.5%, the total yield of p-fluorobenzoyl chloride was 86.7%. The structure of target product was identified by IR,MS and 1H NMR.

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相似文献/References:

[1]方永勤,王兆岗,吕新宇.对氟甲苯液相氧化制备对氟苯甲醛[J].常州大学学报(自然科学版),2011,(02):32.
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备注/Memo

备注/Memo:
作者简介:方永勤(1966-),女,江苏姜堰人,研究员级高级工程师。
更新日期/Last Update: 2012-01-01