[1]周维杰,席海涛,孙小强.含荧光基团透明质酸衍生物的合成及其荧光性能[J].常州大学学报(自然科学版),2013,(04):57-60.[doi:10.3969/j.issn.2095-0411.2013.04.012]
 ZHOU Wei jie,XI Hai tao,SUN Xiao qiang.Synthesis and Fluorescence Properties of Hyaluronic Acid Derivatives Containing Fluorescent Groups[J].Journal of Changzhou University(Natural Science Edition),2013,(04):57-60.[doi:10.3969/j.issn.2095-0411.2013.04.012]
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含荧光基团透明质酸衍生物的合成及其荧光性能()
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常州大学学报(自然科学版)[ISSN:2095-0411/CN:32-1822/N]

卷:
期数:
2013年04期
页码:
57-60
栏目:
出版日期:
2013-09-30

文章信息/Info

Title:
Synthesis and Fluorescence Properties of Hyaluronic Acid Derivatives Containing Fluorescent Groups
作者:
周维杰席海涛孙小强
常州大学 石油化工学院,江苏 常州 213164
Author(s):
ZHOU Wei jieXI Hai taoSUN Xiao qiang
School of Petrochemical Engineering,Changzhou University,Changzhou 213164,China
关键词:
透明质酸 7-羟基-4-甲基香豆素 荧光性能
Keywords:
hyaluronic acid 7-hydroxy-4-methyl coumarin fluorescence performance
分类号:
TQ 201
DOI:
10.3969/j.issn.2095-0411.2013.04.012
文献标志码:
A
摘要:
以透明质酸钠和7-羟基-4-甲基香豆素为原料,合成了具有荧光性能的透明质酸衍生物。通过模拟人体的生理环境,研究了浓度、pH和温度变化对透明质酸衍生物荧光性能的影响。结果表明,透明质酸衍生物荧光强度随浓度的增大而增强,随pH变化其荧光强度变化趋势不明显,较为稳定,随温度的变化其荧光强度基本保持稳定。为以后探索具有药物载体透明质酸在机体内的作用机理及其靶向作用提供良好的实验基础。
Abstract:
The hyaluronic acid derivatives with fluorescence performance were synthesized from sodium hyaluronate and 7-hydroxy-4-methyl coumarin.Then the influences of the concentration, pH and temperature on fluorescence intensity of hyaluronic acid derivatives we

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金项目资助(20872051) 作者简介:周维杰(1987-),男,甘肃陇南人,硕士生; 通讯联系人:席海涛。
更新日期/Last Update: 2013-09-30